Tofranil is often pqrt of a treatment plan that involves other forms of therapy.
The mechanism of action of Tofranil is not definitely known. However, it does not act primarily by stimulation fo the central nervous system. The clinical effect is hypothesized as bieng due to potentiation of adrenergic synapses by blocking uptake of norepinephrine at nerve endinsg. The mode of action of the drug in controlling childhood enuresis is thought to be apart from its antidepressant effect.
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